Dean graduated from Case Western Reserve University in 2016 with a B.S.E. in Chemical Engineering. As an undergraduate, Dean performed research developing high-throughput tools for cartilage tissue engineering in the lab of Dr. Harihara Baskaran. After graduation, he worked on pre-clinical drug development for osteoarthritis at Merrimack Pharmaceuticals in Cambridge, MA, where he was successfully bitten by the biomedical research bug. He matriculated at the Molecular Medicine PhD program at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, where he joined the Scacheri lab in Spring of 2018. Dean is interested in the role transcription factors play in mediating osteosarcoma metastasis. When not in the lab, he likes to bike (slower than Pete), bake, and try all the different restaurants around Cleveland.
Ellen graduated with a B.A. in Biological Sciences from Cornell University in 2017. As an undergraduate, she studied the RAD9-RAD1-HUS1 (9-1-1) DNA checkpoint clamp in Dr. Robert Weiss’s laboratory at Cornell. She also investigated the molecular mechanisms leading to pulmonary metastasis in osteosarcoma in Dr. Chand Khanna’s laboratory at the NIH. After graduation, Ellen entered the CWRU MSTP in 2017, and she is excited to finish her preclinical years and begin working full-time in the Scacheri laboratory in the spring of 2019. Ellen is interested in the intersection of metabolism and epigenetics. Outside of lab, she enjoys watching TV, listening to Korean pop music, and running.
Mac graduated with a B.S. in Chemistry with distinction from Duke University in 2016. As an undergraduate, he performed analytical biochemistry research with Dr. Michael Fitzgerald investigating protein thermodynamics and worked as a research intern with Novartis Vaccines and Diagnostics. After graduation, Mac joined the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University as a Healy and Loop scholar, where he is also working towards an MS in bioinformatics. He is currently investigating the genetic and epigenetic profile of osteosarcomas, with interest in the role of enhancers in osteosarcoma formation and metastasis. In his spare time, Mac enjoys cooking Indian food, playing with his dog (Tucker), spending time with friends and family, and working on his clinical research interests.
Devin graduated with a B.S. in Biology from Syracuse University where she also continued to complete a M.S. degree in the laboratory of Dr. Roy Welch. Her primary thesis work focused on factors influencing cellular differentiation and how populations of cells interact under starvation conditions in the bacterium Myxococcus xanthus. Devin entered the CWRU BSTP program in 2016, and became a member of the Scacheri lab in January 2017. She is currently studying the role of transcription factors in the maintenance of enhancer activity in colon cancer. Outside of lab, she enjoys playing tennis, running, and cooking.
Andrew graduated from Michigan State University with a B.S. in Biochemistry and Molecular Biology in 2014. As an undergraduate, he had several research experiences including exploring the effects of plant metabolites on colon cancer and investigating the molecular basis of epileptogenesis. After graduation, he entered the CWRU MSTP in 2014, and began work full-time in the Scacheri laboratory in 2016. Andrew is co-mentored by Dr. Jeremy Rich of the Cleveland Clinic Lerner Research Institute, and he is currently working on a joint project between the two labs to uncover genomic alterations in cancer can disrupt epigenetic regulation. Outside of the laboratory, he enjoys exploring all that Cleveland has to offer, including frequenting Playhouse Square, the Cuyahoga Valley National Park, and Mitchell’s Ice Cream.
Ian graduated with a B.S in Biology from Carnegie Mellon University in 2012. He performed his undergraduate research in breast cancer biology at the University of Pittsburgh studying the effects of omega-3 fatty acids on tumor growth. After graduating from CMU he studied the transcription elongation factor ELL2 in the context of plasma cell development under Dr. Christine Milcarek at the University of Pittsburgh. After two years Ian was accepted into the BSTP program at Case Western and joined the Scacheri lab in December 2014. He currently studies changes in 3D chromatin architecture in the context of diseases, particularly in osteosarcoma and colon cancer. Outside of lab, Ian enjoys a wide range of intramural sports including soccer, softball, and flag football. He also indulges his technophile urges by keeping up with the latest and greatest gadgets and has already upgraded half of the labs computers.
Stevephen graduated from the University of Maryland with a B.S. in Bioengineering in 2011. He credits his early interest in research to formative summer internships in the laboratories of Dr. Donald Rau (NIH), and Dr. Carl Simon Jr. (NIST), which allowed him to explore the fields of biophysics and tissue engineering, respectively. After college he developed his interest in genomics working as a post-bac in Dr. Henry Levin’s lab (NIH), where he screened for genes important in heterochromatin formation using a DNA transposon to create mutations in the yeast genome. Stevephen joined the CWRU MSTP in 2013, and has been a member of the Scacheri lab since 2015. Working with others in the lab, he is currently investigating the effect of common somatic mutations in enhancers on the development of colorectal cancer. In his free time, Stevephen likes to listen to music, watch TV, read, and play basketball.